Als een van de artiesten met wereldwijd de meest verkochte albums aller tijden hebben de Backstreet Boys een enorm aantal prijzen gewonnen in de muziekindustrie.
Hieronder volgt een lijst met een aantal van de prijzen die zij gewonnen hebben:
| Prijs | Categorie | Jaar |
| Smash Hits Award | Best New Tour Act | 1995 |
| TMF Award | Beste nieuwkomers | 1996 |
| MTV Europe Music Award | Best Newcomers | 1996 |
| TMF Award | Beste album (Backstreet Boys) | 1997 |
| TMF Award | Beste single (Quit Playin’ Games) | 1997 |
| TMF Award | Beste videoclip (Get Down) | 1997 |
| Viva Comet Award | Best Newcomers | 1997 |
| Diamond Award | Backstreet Boys certified as a Diamond album in Canada (1,000,000 units sold) | 1997 |
| TMF Award | Beste album (Backstreet’s Back) | 1998 |
| TMF Award | Beste single (As Long As You Love Me) | 1998 |
| TMF Award | Beste live-act | 1998 |
| MTV Video Music Award | Best Group Video “Everybody” | 1998 |
| MuchMusic Video Award | People’s Choice Favorite International Group | 1998 |
| World Music Award | World’s Best-Selling Dance Artist/Group | 1998 |
| Echo Award | Best International Group | 1998 |
| Viva Comet Award | Best Newcomers | 1998 |
| Diamond Award | Backstreet’s Back certified as a Diamond album in Canada (1,000,000 units sold) | 1998 |
| TMF Award | Beste live-act | 1999 |
| Billboard Music Award | Album of the Year “Millennium” | 1999 |
| Billboard Music Award | Artist of the Year | 1999 |
| Billboard Music Award | Album Artist Duo/Group of the Year for “Millennium” | 1999 |
| Billboard Music Award | Album Artist of the Year for “Millennium” | 1999 |
| MTV Europe Music Award | Best Group | 1999 |
| MTV Video Music Award | Viewer’s Choice for “I Want It That Way” | 1999 |
| MuchMusic Video Award | People’s Choice International Group | 1999 |
| Blimp Award | Favorite Song for “Everybody” | 1999 |
| Teen Choice Award | Music Video of the Year for “All I Have To Give” | 1999 |
| VIVA Comet Award | Band Of The Year | 1999 |
| VIVA Comet Award | Spectators-Comet Viva | 1999 |
| Diamond Award | Backstreet Boys certified as a Diamond album in the U.S.(10,000,000 units sold) | 1999 |
| Diamond Award | Millennium certified as a Diamond album in Canada (1,000,000 units sold). | 1999 |
| Diamond Award | Millennium certified as a Diamond album in the U.S. (10,000,000 units sold) | 1999 |
| TMF Award | Beste live-act | 2000 |
| ALMA Award | The Ten Outstanding Music Video Performers for “I Want It That Way | 2000 |
| American Music Award | Favorite Band/Duo/Group for “Millennium” | 2000 |
| Blockbuster Entertainment Award | Favorite Pop Group | 2000 |
| Blockbuster Entertainment Award | Favorite CD | 2000 |
| BMI Pop Award | 50 Most Performed Songs for “I will never break your heart” | 2000 |
| Juno Award | Best-Selling Album (foreign or domestic) for “Millennium” | 2000 |
| MTV Europe Music Award | Best Group | 2000 |
| Blimp Award | Favorite Musical Group | 2000 |
| NRJ Radio Award | Best International Group | 2000 |
| People’s Choice Award | Favorite Musical Group or Band | 2000 |
| Radio Music Award | Radio Slow Dance Song of the Year for “Show Me The Meaning Of Being Lonely” | 2000 |
| Teen Choice Award | Album of the Year for “Millennium” | 2000 |
| World Music Award | Best Selling Pop Group | 2000 |
| World Music Award | Best American Group | 2000 |
| World Music Award | Best Selling R&B Group | 2000 |
| World Music Award | Best Selling Dance Group | 2000 |
| TMF Award | Beste popgroep | 2001 |
| American Music Award | Favorite Pop/Rock Band/Duo/Group for “Black & Blue” | 2001 |
| TMF Award | Beste live-act | 2002 |
| RIAJ | 17th Japan Gold Disc Award 2002 | 2002 |
| MTV Asia Award | Favourite Pop Act | 2006 |